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pentobarbital will lower the level or result of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will minimize the level or outcome of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Double brexpiprazole dose in excess of one